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JNJ-37822681 dihydrochloride

CAS No. 2108806-02-4

JNJ-37822681 dihydrochloride ( —— )

产品货号. M26266 CAS No. 2108806-02-4

JNJ-37822681 dihydrochloride is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥940 有现货
10MG ¥1320 有现货
25MG ¥2187 有现货
50MG ¥3224 有现货
100MG ¥4803 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    JNJ-37822681 dihydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    JNJ-37822681 dihydrochloride is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.
  • 产品描述
    JNJ-37822681 dihydrochloride is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor. JNJ-37822681 dihydrochloride shows a moderate binding affinity for the dopamine D2L receptor with a Ki of 158 nM.(In Vivo):JNJ-37822681 dihydrochloride occupied D2 receptors in rat brain at relatively low doses (ED50 = 0.39 mg/kg) and was effective in animal models of psychosis (e.g., inhibition of apomorphine-induced stereotypy or D-amphetamine/phencyclidine-induced hyperlocomotion).
  • 同义词
    ——
  • 通路
    GPCR/G Protein
  • 靶点
    Dopamine Receptor
  • 受体
    HBV
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2108806-02-4
  • 分子量
    445.3
  • 分子式
    C17H19Cl2F5N4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.Cl.Fc1ccc(CN2CCC(CC2)Nc2ccc(nn2)C(F)(F)F)cc1F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Danni Colledge, et al. The Novel Antiviral Agent Inarigivir Inhibits Both Nucleos(t)ide Analogue and Capsid Assembly Inhibitor Resistant HBV in vitro.
产品手册
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